Therapeutic Antibody Development and Modalities
At RoukenBio, our multidisciplinary team of experts is dedicated to supporting the development of various therapeutic modalities, each with its own unique challenges and opportunities. Our deep expertise across different therapeutic areas, combined with our state-of-the-art assay platforms and custom development capabilities, makes us the perfect partner for your drug development journey.
Modalities We Support
Whether you are advancing therapeutic antibodies, engineered cell therapies, or small-molecule immunomodulators, our scientists build the bespoke in vitro models needed to reveal mechanism, potency, safety, and functional biology. With cross-functional expertise in immunology, bioassay development, and cell engineering we design the right assay system for your modality to drive your project forward reaching the clinic faster.
Explore how we support your modality:
Large Molecules
We use engineered and primary human immune cells to characterise binding, signalling, effector function, receptor engagement, cytokine modulation and other immunological mechanisms. Helping you select and differentiate candidates, understand mechanism of action, and generate data to support IND-enabling packages.
Cell Therapy
For developers of adoptive cell therapies, RoukenBio builds customised in vitro models using both donor-derived immune cells and bespoke engineered cell systems. We assess cell potency, activation, cytotoxicity and immunological safety, giving you human-relevant insight into how your cell therapy behaves in controlled immune environments.
Small Molecules
At RoukenBio, we evaluate small-molecule modulators of immune pathways using in vitro cellular assays. We quantify pathway inhibition/activation, downstream signalling, cytokine release profiles, and immune-cell function to help identify the most promising candidates.
FAQs
As a Drug Discovery CRO with special focus on developing bespoke assay solutions and innovative methods toward unique drug development needs, we tailor solutions to various therapeutic modalities covering immunology, immune-oncology, autoimmune disease, inflammation, allergy and more.
The type of molecules our cross-functional teams work with are diverse. We cover all immunotherapy and antibody-based molecules and therapeutic modalities like;
- Monoclonal antibodies (mAbs)
- Bispecific antibodies (BsAbs)
- Multi-specifics, multispecific molecules
- Immunocytokines, antibody-cytokine fusion proteins
- Cell therapies
- Targeted protein degraders (TPDs)
- Small molecules
- Large molecules
- Oligonucleotide-based nanoparticles
- Complex biologics
- Peptides and more
Our assay platforms, methodologies and custom solutions have been applied to all the drug classes listed above and the list is constantly growing.
Propel drug discovery breakthroughs with RoukenBio
Difficulty doesn’t deter us; it inspires us. Give us a problem, and we’ll find your solution. Our versatile specialists embrace every obstacle as an opportunity to showcase our innovative thinking and problem-solving prowess.
Access our Capabilities brochure
