In Vitro and Cell-Based Assay Development
We design and execute in vitro cell-based assays that give you clear, functional insights into your drug candidate. Whether you need to understand mechanism of action, measure potency, or predict immune-related safety, our assays provide data you can trust to make confident decisions.
Explore our innovative immune cell assays and platforms, offering tailored solutions to drive your research forward with precision and reliability.
Our Assay Capabilities
Our scientists combine deep immunology expertise with advanced cell engineering capabilities to create bespoke, reproducible systems that mirror human biology. Every assay is designed to help you select and optimise the most promising therapeutic candidates faster and with greater confidence.
Explore our Cell-Based Assay Services
RoukenBio’s in vitro assay development portfolio supports functional characterisation, in vitro pharmacology, and safety assessment across a range of therapeutic areas, including immuno-oncology, inflammation, allergy and autoimmunity.
Custom Cell Engineering
We build the cell based tools and models that you need to understand your molecule. Our custom-engineered cells and cell lines enable you to uncover binding, signalling, and mechanism-of-action insights with precision and reproducibility.
3D Cell Assays
Gain more translational results before moving in vivo. Our patient explants and 3D cell systems recreate the complexity of human tissue, helping you evaluate efficacy and behaviour in a physiologically relevant environment.
Immune Cell Assays
Understand how your therapeutic candidates interact with human immune cell subsets. Using PBMCs and whole blood from healthy and disease state donors, our assays provide data on binding, functionality, efficacy, safety, selectivity, and mechanisms of action.
Immunogenicity and Safety Assessments
De-risk your drug development pipeline early. We identify potential immune activation or cytokine release risks using predictive in vitro systems, supporting safer and faster progression to the clinic.
Bioanalytical Assessments
Validate quality with confidence. Our detailed biophysical and cell based analyses confirm functionality, activity, and comparability throughout development and manufacturing.
FAQs
We provide a complete range of in vitro cell-based assays, from mechanistic and potency studies to immunogenicity and safety assessments, all tailored to your molecule and target biology. We employ a range of cell types; primary immune cells, reporter cell lines, immortalised cells, non-immune primary cells and disease state donor cells.
Propel drug discovery breakthroughs with RoukenBio
Difficulty doesn’t deter us; it inspires us. Give us a problem, and we’ll find your solution. Explore our cell-based assay development capabilities and assay portfolio in our Capabilities brochure.
Access our Capabilities brochure
