Immuno-Oncology

Immuno-oncology (I-O) represents a groundbreaking approach in cancer treatment, leveraging the body’s immune system to identify and eliminate tumour cells. This innovative field focuses on modulating the immune response to first recognise, then target cancer, fundamentally altering the tumour microenvironment to promote anti-tumour activity.

Leveraging our I-O expertise, we have built up an array of assay systems to recreate immune cell interactions in the tumour microenvironment, closely mimicking physiological processes and advancing your novel therapeutic modality.

Autoimmunity and Inflammation

Autoimmune disease arises when a dysregulated immune system mistakenly targets and attacks the body, leading to chronic inflammation and tissue damage. The complex mechanisms underlying disease have revealed novel targets for modern therapeutic interventions that modulate the immune response, moving beyond immunosuppression by traditional therapies. 

At RoukenBio, our profound knowledge in translational immunology and autoimmune pathophysiology enables us to support the development of innovative therapies that modulate immune responses to restore balance and alleviate disease symptoms. Our advisory approach, backed by decades of collective experience, has led to the creation of an array of assay systems that recreate autoimmune environments, closely mirroring physiological processes. 

Allergy

Allergy is an exaggerated immune response to substances that are typically harmless. Affected individuals experience a range of responses depending upon the severity of their allergy. These can range from mild symptoms such as sneezing, itching and coughing to severe and life-threatening responses such as anaphylaxis. Current therapies focus on broad suppression of the immune response but novel therapies that specifically target the underlying mechanisms driving allergy offer the opportunity to provide better treatments. At RoukenBio, our scientific experts have extensive experience in the biology of allergic responses and in the support of innovative therapy development.