Scientific Resources

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T cell exhaustion poster.png

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28 October 2026

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5 min read

In Vitro Antigen-Specific T Cell Exhaustion Model for Immunomodulators

This research poster presents a human antigen-specific in vitro CD8+ T-cell exhaustion model designed to replicate chronic tumour antigen stimulation. By assessing inhibitory receptor expression, cytokine production and cytolytic activity, the model supports investigation of T-cell exhaustion and evaluation of candidate immunomodulators.

Human patient-derived models for translational immuno-oncology and inflammation drug discovery.png

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26 October 2026

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5 min read

Human patient-derived models for translational immuno-oncology and inflammation drug discovery

This research poster presents two complementary human patient-derived ex vivo platforms for immuno-oncology and inflammation drug discovery: a colorectal cancer tumoroid model incorporating autologous immune and stromal cells, and an intestinal biopsy model for inflammatory bowel disease. By capturing patient-specific heterogeneity and generating functional responses to therapeutic intervention, these models support translational drug discovery and predictive biomarker identification.

202608 - Development of a high-throughput multimodal patient-derived platform integrating autologous fibroblasts and tumour-infiltrating lymphocytes for colorectal cancer drug discovery .png

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17 August 2026

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4 min read

Development of a high-throughput multimodal patient-derived platform integrating autologous fibroblasts and tumourinfiltrating lymphocytes for colorectal cancer drug discovery

This research poster presents a high-throughput, patient-derived colorectal cancer tumoroid platform incorporating autologous fibroblasts and tumour-infiltrating lymphocytes. By combining genomic, gene-expression and drug-response data, the model captures patient-specific tumour heterogeneity and supports translational drug discovery, predictive biomarker identification and immunotherapy research.

Complex Bioassays Bridging Analytics and Clinical Relevance in Biosimilar Development.png

https://website-content.rouken.bio/research_poster_039a1b785f.svgResearch Posters

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30 June 2026

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4 min read

Complex Bioassays: Bridging Analytics and Clinical Relevance in Biosimilar Development

This poster illustrates how complex primary cell-based assays contribute to biosimilar comparability by addressing key mechanisms of action and fulfilling roles central to regulatory expectations integrating biological activity assessment, indication extrapolation and the linkage of analytical data with clinical relevance.

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