Preclinical Research Services at RoukenBio
Our preclinical research service areas, including disease modelling, target validation, in vitro pharmacology, immunotoxicology, product characterisation, cell engineering, and biosimilars leverage our expertise and advanced methodologies to support all stages of therapeutic development and drive your drug development projects forward.
Access our Capabilities brochureOur Immunology Research Service Areas
We specialise in cutting-edge assay design using advanced platforms, patented technologies, and state-of-the-art equipment. With a team of experts, we address the challenges of evolving therapeutic modalities, making us the ideal partner for your development needs.
Explore our core immunology research services for more information.
Disease Modelling and Target Validation
Advance with confidence. We design bespoke in vitro disease models that reflect complex immune interactions, so you can validate targets and define mechanisms of action to prioritise the most promising therapeutic candidates.
In Vitro Pharmacology
Understand your molecule’s true potential. Our in vitro pharmacology assays reveal potency, efficacy, and signalling data that guide rational design, helping you refine biologic and immunotherapeutic candidates before clinical testing.
Immunotoxicology
Mitigate immune-related risks early. Using primary human immune cells and cell-based systems, our predictive immunotoxicology assays identify potential safety concerns to support smarter, safer development decisions.
Product Characterization: Function and Binding
We characterise our products through detailed analysis of their biological function and molecular binding. Functional studies confirm activity, specificity, and potency, while binding assays define affinity, kinetics, and target engagement. Together, these assessments ensure consistent performance and verified mechanism of action.
Molecular Biology and Cell Engineering
Get the research tools you need for discovery. From vector design to stable cell line generation, we create custom, reproducible systems that empower you to interrogate mechanisms and advance your research.
Biosimilars
Achieve confidence in comparability. Our analytical and functional biosimilar assays are deigned to deliver data to demonstrate biosimilarity in support of regulatory submissions. Combined with complex primary immune cell assays that confirm mechanism of action and reduce the need for clinical efficacy studies, we de-risk development and accelerate approval.
FAQs
Our preclinical research services support therapeutic development from early discovery through to IND-enabling studies, with some clinical stage for information-only studies. We can help as early as target biology validation, but often we join the drug discovery process at the functional screening to in vitro pharmacology stages. We can assist in triaging of molecules to in-depth functional characterisation of your lead asset. Add to this product characterisation and immunotoxicity assessments, and we provide the robust data package you need to make confident go/no-go decisions.
Propel drug discovery breakthroughs with RoukenBio
Difficulty doesn’t deter us; it inspires us. Give us a problem, and we’ll find your solution. Our versatile specialists embrace every obstacle as an opportunity to showcase our innovative thinking and problem-solving prowess.
Access our Capabilities brochure
