We offer a range of assays to explore NK cell function and therapeutic potential.
Access OUR PRESENTATIONNatural killer (NK) cells are best known for their roles in recognition and killing of virally infected cells and tumour immunosurveillance. Their activity is regulated by a balance of germline encoded activating and inhibitory immunoreceptors that allow them to directly respond to cellular stress, infection or malignancy. Their ability to kill tumour cells makes them an attractive target in cancer immunotherapy.
NK cell mediated ADCC
NK cell expansion and banking
NK cell activation
Assess the ability of NK cells to engage and kill antibody-coated target cells. This assay measures the effectiveness of therapeutic antibodies in directing NK cells to eliminate target cells applicable to immuno-oncology, therapeutic antibody development and infectious disease research.
Expand and cryopreserve NK cells from healthy donors for use in your assays. NK cell banks provide a reliable source of NK cells for various research and therapeutic applications such as cell therapy development, standardized research assays and preclinical studies.
The impact of therapeutics on the phenotype of NK cells can be assessed using our NK cell activation assay. This flow cytometry based assay can measure changes in the expression of the surface proteins that are associated with NK cell activation.
We address the challenges of acquiring sufficient quantities of NK cells for your therapeutic assessments.
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