Research Posters
10 November 2026
|5 min read
This research poster presents an integrated, human-relevant assay cascade for antibody-drug conjugate (ADC) evaluation, connecting target engagement and intracellular payload delivery with target-density dependence, tumour-cell killing, Fc-mediated immune activity and response within the tumour microenvironment. By combining controlled cellular models, primary human immune assays and patient-derived tumour models, the approach generates mechanism-linked insights to support more informed ADC candidate ranking and lead selection
Research Posters
4 November 2026
|5 min read
This research poster presents a modular, patient-derived 3D colorectal cancer model incorporating tumoroids, tumour-infiltrating lymphocytes (TILs) and cancer-associated fibroblasts (CAFs). By recreating key immune and stromal interactions within the tumour microenvironment and enabling assessment of therapeutic responses, the platform provides a translational approach for evaluating novel immuno-oncology therapeutics.
Research Posters
28 October 2026
|5 min read
This research poster presents a human antigen-specific in vitro CD8+ T-cell exhaustion model designed to replicate chronic tumour antigen stimulation. By assessing inhibitory receptor expression, cytokine production and cytolytic activity, the model supports investigation of T-cell exhaustion and evaluation of candidate immunomodulators.
Research Posters
26 October 2026
|5 min read
This research poster presents two complementary human patient-derived ex vivo platforms for immuno-oncology and inflammation drug discovery: a colorectal cancer tumoroid model incorporating autologous immune and stromal cells, and an intestinal biopsy model for inflammatory bowel disease. By capturing patient-specific heterogeneity and generating functional responses to therapeutic intervention, these models support translational drug discovery and predictive biomarker identification.
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